Malabaricone B
Product Specifications
UNSPSC Description
Malabaricone B, a naturally occurring plant phenolic, is an orally active α-glucosidase inhibitor with an IC50 of 63.7 μM. Malabaricone B has anticancer, antimicrobial, anti-oxidation and antidiabetic activities[1][2][3].
Target Antigen
Apoptosis; Glycosidase
Type
Natural Products
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/malabaricone-b.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(O)C=CC=C1O)CCCCCCCCC2=CC=C(O)C=C2
Molecular Weight
342.43
References & Citations
[1]Mrityunjay Tyagi, et al. Spice-derived phenolic, malabaricone B induces mitochondrial damage in lung cancer cells via a p53-independent pathway. Food Funct. 2018 Nov 14;9(11):5715-5727.|[2]K Y Orabi, et al. Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans). J Nat Prod. May-Jun 1991;54(3):856-9. |[3]B Prabha, et al. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem. 2018 Jul 23;26(12):3461-3467.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N8517/Malabaricone-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N8517/Malabaricone-B-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
63335-24-0
Available Sizes
Curated Selection
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