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Acp2 (NM_007387) Mouse Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Two isoforms are predicted to be produced from the same mRNA by the use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]

Synonyms

Acp; Acp-2; LAP

Gene ID

11432

UniProt

P24638, Q3UZN1

Accession Number mRNA

NM_007387

Chromosomal Location

2 50.54 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Acp2

Species

Mouse

Protein ID

NP_031413

Overview

Purified recombinant protein of Mouse acid phosphatase 2, lysosomal (Acp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11432

Uniprot URL

https://www.uniprot.org/uniprot/P24638

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007387

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_031413

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