Lingo1 (NM_181074) Mouse Recombinant Protein
Product Specifications
Background
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity) . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.[UniProtKB/Swiss-Prot Function]
Synonyms
4930471K13Rik; AV148400; LERN1; LINGO-1; Lrrn6a; UNQ201
Gene ID
235402
UniProt
Q9D1T0
Accession Number mRNA
NM_181074
Chromosomal Location
9 B
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
69.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Lingo1
Species
Mouse
Protein ID
NP_851419
Overview
Purified recombinant protein of Mouse leucine rich repeat and Ig domain containing 1 (Lingo1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/235402
Uniprot URL
https://www.uniprot.org/uniprot/Q9D1T0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_181074
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_851419
Curated Selection
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