Plekhg6 (NM_198604) Mouse Recombinant Protein
Product Specifications
Background
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
BC026778; Gm155
Gene ID
213522
UniProt
Q8R0J1
Accession Number mRNA
NM_198604
Chromosomal Location
6 F3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
89.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Plekhg6
Species
Mouse
Protein ID
NP_941006
Overview
Purified recombinant protein of Mouse pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (Plekhg6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/213522
Uniprot URL
https://www.uniprot.org/uniprot/Q8R0J1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198604
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_941006
Curated Selection
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