KSPWFTTL

KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].

Product Specifications

CAS Number

[153049-05-9]

UNSPSC

12352209

Target

MHC

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kspwfttl.html

Purity

99.60

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@@H](N)CCCCN)=O)=O)N[C@H](C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)CC2=CC=CC=C2)=O)CC3=CNC4=CC=CC=C34

Molecular Formula

C48H70N10O12

Molecular Weight

979.13

References & Citations

[1]White HD, et, al. An immunodominant Kb-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR623 that restores susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. J Virol. 1994 Feb;68 (2) :897-904.|[2]Rich RF, et, al. Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4 (+) and CD8 (+) antiviral T cells by viral antigen-positive veto cells. J Virol. 1999 May;73 (5) :3826-34.