Dgkd (NM_177646) Mouse Recombinant Protein
Product Specifications
Background
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:17021016) . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:17021016) . By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development (PubMed:17021016) . May also regulate clathrin-dependent endocytosis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AI841987; D330025K09; dgkd-2; DGKdelta
Gene ID
227333
UniProt
E9PUQ8
Accession Number mRNA
NM_177646
Chromosomal Location
1 D
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
135.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dgkd
Species
Mouse
Protein ID
NP_808314
Overview
Purified recombinant protein of Mouse diacylglycerol kinase, delta (Dgkd), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/227333
Uniprot URL
https://www.uniprot.org/uniprot/E9PUQ8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177646
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_808314
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