Gcsam (NM_001159297) Mouse Recombinant Protein
Product Specifications
Background
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.[UniProtKB/Swiss-Prot Function]
Synonyms
Gcet; Gcet2; M17; M17-L
Gene ID
14525
UniProt
Q6RFH4
Accession Number mRNA
NM_001159297
Chromosomal Location
16 B5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gcsam
Species
Mouse
Protein ID
NP_001152769
Overview
Purified recombinant protein of Mouse germinal center associated, signaling and motility (Gcsam), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14525
Uniprot URL
https://www.uniprot.org/uniprot/Q6RFH4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001159297
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001152769
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