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Cdh1 (NM_009864) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8. [provided by RefSeq, Oct 2015]

Overview

Purified recombinant protein of Mouse cadherin 1 (Cdh1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AA960649; ARC-1; E-ca; E-cad; E-cadh; Eca; Ecad; L-C; L-CAM; Um; UVO

Gene ID

12550

UniProt

P09803, A0A0R4IZW5

Accession Number mRNA

NM_009864

Chromosomal Location

8 53.18 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

98.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Cdh1

Species

Mouse

Protein ID

NP_033994

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/12550

Uniprot URL

https://www.uniprot.org/uniprot/P09803

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_009864

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_033994

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