P2X2 (P2RX2) (NM_170682) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]

Overview

Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), V60L mutant of transcript variant 1, 20 ug

Synonyms

DFNA41; P2X2

Gene ID

22953

UniProt

Q9UBL9, Q32MC3

Accession Number mRNA

NM_170682

Chromosomal Location

12q24.33

Expression System

HEK293

Tag

C-Myc/DDK

Related Pathways

Calcium signaling pathway, Neuroactive ligand-receptor interaction

Field of Research

Calcium signaling pathway, Neuroactive ligand-receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Ion Channels: ATP Receptors, Transmembrane

Molecular Weight

51.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.