SNAP43 (SNAPC1) (NM_003082) Human Recombinant Protein

Product Specifications

Background

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Homo sapiens small nuclear RNA activating complex, polypeptide 1, 43kDa (SNAPC1), with N-terminal HIS tag, expressed in E.Coli, 50ug

Synonyms

PTFgamma; SNAP43

Gene ID

6617

UniProt

Q16533, B2RC42

Accession Number mRNA

NM_003082

Chromosomal Location

14q23.2

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

Function

Transcription Factors

Molecular Weight

42.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.