ARPC4 (NM_005718) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]
Synonyms
ARC20; P20-ARC
Gene ID
10093
UniProt
P59998
Accession Number mRNA
NM_005718
Chromosomal Location
3p25.3
Expression System
E. coli
Tag
N-His
Related Pathways
Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
Field of Research
Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Molecular Weight
19.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARPC4
Species
Human
Protein ID
NP_005709
Overview
Purified recombinant protein of Human actin related protein 2/3 complex, subunit 4, 20kDa (ARPC4), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10093
Uniprot URL
https://www.uniprot.org/uniprot/P59998
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005718
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005709
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