SNIP1 (NM_024700) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED) . [provided by RefSeq, Mar 2012]
Overview
Purified recombinant protein of Human Smad nuclear interacting protein 1 (SNIP1), full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Synonyms
PML1; PMRED
Gene ID
79753
UniProt
Q8TAD8, B1AK66
Accession Number mRNA
NM_024700
Chromosomal Location
1p34.3
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Molecular Weight
73.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SNIP1
Species
Human
Protein ID
NP_078976
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79753
Uniprot URL
https://www.uniprot.org/uniprot/Q8TAD8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024700
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078976
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