LYPD1 (NM_001077427) Human Recombinant Protein
Product Specifications
Background
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.[UniProtKB/Swiss-Prot Function]
Synonyms
LYPDC1; PHTS
Gene ID
116372
UniProt
Q8N2G4
Accession Number mRNA
NM_001077427
Chromosomal Location
2q21.2
Expression System
E. coli
Tag
N-GST and C-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
Function
Druggable Genome, Transmembrane
Molecular Weight
37.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LYPD1
Species
Human
Protein ID
NP_001070895
Overview
Purified recombinant protein of Human LY6/PLAUR domain containing 1 (LYPD1), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/116372
Uniprot URL
https://www.uniprot.org/uniprot/Q8N2G4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001077427
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001070895
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