Inhibin alpha (INHA) (NM_002191) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]
Synonyms
A-inhibin subunit; inhibin, alpha; inhibin alpha subunit
Gene ID
3623
UniProt
P05111
Accession Number mRNA
NM_002191
Chromosomal Location
2q35
Expression System
E. coli
Tag
N-His-Trx
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Secreted Protein
Molecular Weight
35.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
INHA
Species
Human
Protein ID
NP_002182
Overview
Purified recombinant protein of Human inhibin, alpha (INHA), Ser233-Ile366, with N-terminal His-Trx tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3623
Uniprot URL
https://www.uniprot.org/uniprot/P05111
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002191
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002182
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