TAF1B (NM_005680) Human Recombinant Protein
Product Specifications
Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Synonyms
MGC:9349; RAF1B; RAFI63; SL1; TAFI63
Gene ID
9014
UniProt
Q53T94
Accession Number mRNA
NM_005680
Chromosomal Location
2p25.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Transcription Factors
Molecular Weight
23.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TAF1B
Species
Human
Protein ID
NP_005671
Overview
Purified recombinant protein of Human TATA box binding protein (TBP) -associated factor, RNA polymerase I, B, 63kDa (TAF1B), Met1-Lys208, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9014
Uniprot URL
https://www.uniprot.org/uniprot/Q53T94
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005680
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005671
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