Propranolol
Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].
Product Specifications
CAS Number
[525-66-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Adrenergic Receptor; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Cardiovascular Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/propranolol.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(COC1=C2C=CC=CC2=CC=C1)CNC(C)C
Molecular Formula
C16H21NO2
Molecular Weight
259.34
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
β adrenergic receptor
Citation 01
Available Sizes
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