CD3H Rabbit mAb (AMR12487N)
Product Specifications
Background
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CD3-ZETA; CD3H; CD3Q; CD3Z; IMD25; T3Z; TCRZ
Gene ID
919
UniProt
P20963
Cellular Locus
Membrane, Single-pass type I membrane protein
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 FC 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: kDa Observed MW: 16KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD3H Rabbit mAb (APR18352N7) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=919
Uniprot URL
https://www.uniprot.org/uniprot/P20963
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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