Bcl 6 (BCL6) Mouse Monoclonal Antibody [Clone ID: LBI6C7]
Product Specifications
Background
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Synonyms
BCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Gene Name
Homo sapiens BCL6 transcription repressor (BCL6), transcript variant 1, mRNA.
Gene ID
604
UniProt
P41182
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BCL6
Overview
Carrier-free (BSA/glycerol-free) BCL6 mouse monoclonal antibody, clone LBI6C7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=604
Uniprot URL
https://www.uniprot.org/uniprot/P41182
Curated Selection
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