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NUMB Mouse Monoclonal Antibody [Clone ID: LBI3E5]

Product Specifications

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) NUMB mouse monoclonal antibody, clone LBI3E5

Synonyms

C14orf41; c14_5527; S171

Gene Name

Homo sapiens NUMB endocytic adaptor protein (NUMB), transcript variant 2, mRNA.

Gene ID

8650

UniProt

P49757

Conjugation

Unconjugated

Related Pathways

Notch signaling pathway

Field of Research

Notch signaling pathway

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

NUMB

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=8650

Uniprot URL

https://www.uniprot.org/uniprot/P49757

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