PTOP (ACD) Mouse Monoclonal Antibody [Clone ID: LBI2B1]

Product Specifications

Background

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) ACD mouse monoclonal antibody, clone LBI2B1

Synonyms

PIP1; PTOP; TINT1; TPP1

Gene Name

Homo sapiens ACD shelterin complex subunit and telomerase recruitment factor (ACD), transcript variant 1, mRNA.

Gene ID

65057

UniProt

Q96AP0

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.