UNG Mouse Monoclonal Antibody [Clone ID: LBI1F8]

Product Specifications

Background

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) UNG mouse monoclonal antibody, clone LBI1F8

Synonyms

DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15

Gene Name

Homo sapiens uracil DNA glycosylase (UNG), transcript variant 2, mRNA.

Gene ID

7374

UniProt

P13051

Conjugation

Unconjugated

Related Pathways

Base excision repair, Primary immunodeficiency

Field of Research

Base excision repair, Primary immunodeficiency

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.