SQSTM1 Mouse Monoclonal Antibody [Clone ID: LBI5D5]

Product Specifications

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

Overview

Carrier-free (BSA/glycerol-free) SQSTM1 mouse monoclonal antibody, clone LBI5D5

Synonyms

A170; OSIL; p60; p62; p62B; PDB3; ZIP3

Gene Name

Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1, mRNA.

Gene ID

8878

UniProt

Q13501

Conjugation

Unconjugated

Dilution

WB 1:500~2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.