USP5 Mouse Monoclonal Antibody [Clone ID: LBI2F5]
Product Specifications
Background
Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]
Synonyms
ISOT
Gene Name
Homo sapiens ubiquitin specific peptidase 5 (USP5), transcript variant 2, mRNA.
Gene ID
8078
UniProt
P45974
Conjugation
Unconjugated
Dilution
WB: 1:200 - 1:1000, IHC 1:50, IF 1:100
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Protease
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
USP5
Overview
Carrier-free (BSA/glycerol-free) USP5 mouse monoclonal antibody, clone LBI2F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8078
Uniprot URL
https://www.uniprot.org/uniprot/P45974
Curated Selection
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