Periostin (POSTN) Mouse Monoclonal Antibody [Clone ID: LBI1A1]

Product Specifications

Background

Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein (BMP2) . Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.

Overview

Carrier-free (BSA/glycerol-free) Periostin mouse monoclonal antibody, clone LBI1A1

Synonyms

OSF-2; OSF2; PDLPOSTN; PN

Gene Name

Homo sapiens periostin (POSTN), transcript variant 1, mRNA.

Gene ID

10631

UniProt

Q15063

Conjugation

Unconjugated

Dilution

WB 1:500, IF 1:100

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.