IL2 Receptor beta (IL2RB) Mouse Monoclonal Antibody [Clone ID: LBI1D12]

Product Specifications

Background

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) IL2RB mouse monoclonal antibody, clone LBI1D12

Synonyms

CD122; IL15RB; P70-75

Gene Name

Homo sapiens interleukin 2 receptor subunit beta (IL2RB), transcript variant 1, mRNA.

Gene ID

3560

UniProt

P14784

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.