Plasminogen (PLG) Mouse Monoclonal Antibody [Clone ID: LBI4F5]

Product Specifications

Background

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Overview

Carrier-free (BSA/glycerol-free) PLG mouse monoclonal antibody, clone LBI4F5

Synonyms

DKFZp779M0222

Gene Name

Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Gene ID

5340

UniProt

P00747

Conjugation

Unconjugated

Related Pathways

Complement and coagulation cascades, Neuroactive ligand-receptor interaction

Field of Research

Complement and coagulation cascades, Neuroactive ligand-receptor interaction

Dilution

IHC 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Protease, Secreted Protein

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.