Plasminogen (PLG) Mouse Monoclonal Antibody [Clone ID: LBI4F5]
Product Specifications
Background
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Synonyms
DKFZp779M0222
Gene Name
Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.
Gene ID
5340
UniProt
P00747
Conjugation
Unconjugated
Related Pathways
Complement and coagulation cascades, Neuroactive ligand-receptor interaction
Field of Research
Complement and coagulation cascades, Neuroactive ligand-receptor interaction
Dilution
IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Protease, Secreted Protein
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PLG
Overview
Carrier-free (BSA/glycerol-free) PLG mouse monoclonal antibody, clone LBI4F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5340
Uniprot URL
https://www.uniprot.org/uniprot/P00747
Curated Selection
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