POLR2A Mouse Monoclonal Antibody [Clone ID: LBI1E5]
Product Specifications
Background
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Synonyms
HRPB220; hsRPB1; POLR2; POLRA; RPB1; RPBh1; RpIILS; RPO2; RPOL2
Gene Name
Homo sapiens RNA polymerase II subunit A (POLR2A), mRNA.
Gene ID
5430
UniProt
P24928
Conjugation
Unconjugated
Related Pathways
Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
Field of Research
Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
Dilution
WB 1:2000, IHC 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
POLR2A
Overview
Carrier-free (BSA/glycerol-free) POLR2A mouse monoclonal antibody, clone LBI1E5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5430
Uniprot URL
https://www.uniprot.org/uniprot/P24928
Curated Selection
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