Translin (TSN) Mouse Monoclonal Antibody [Clone ID: LBI1B5]

Product Specifications

Background

This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Overview

Carrier-free (BSA/glycerol-free) TSN mouse monoclonal antibody, clone LBI1B5

Synonyms

BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN

Gene Name

Homo sapiens translin (TSN), transcript variant 1, mRNA.

Gene ID

7247

UniProt

Q15631

Conjugation

Unconjugated

Dilution

WB 1:500~2000, IHC 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.