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Mesothelin (MSLN) Mouse Monoclonal Antibody [Clone ID: LBI2E5]

Product Specifications

Background

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Synonyms

MPF; SMRP

Gene Name

Homo sapiens mesothelin (MSLN), transcript variant 1, mRNA.

Gene ID

10232

UniProt

Q13421

Conjugation

Unconjugated

Dilution

WB 1:500

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Secreted Protein, Transmembrane

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

MSLN

Overview

Carrier-free (BSA/glycerol-free) MSLN mouse monoclonal antibody, clone LBI2E5

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=10232

Uniprot URL

https://www.uniprot.org/uniprot/Q13421

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