TANK Mouse Monoclonal Antibody [Clone ID: LBI1G2]
Product Specifications
Background
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Synonyms
I-TRAF; ITRAF; TRAF2
Gene Name
TRAF family member associated NFKB activator
Gene ID
10010
UniProt
Q92844
Conjugation
Unconjugated
Related Pathways
RIG-I-like receptor signaling pathway
Field of Research
RIG-I-like receptor signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500~2000, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TANK
Overview
TANK mouse monoclonal antibody, clone LBI1G2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10010
Uniprot URL
https://www.uniprot.org/uniprot/Q92844
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