Melanophilin (MLPH) Mouse Monoclonal Antibody [Clone ID: LBI6E3]
Product Specifications
Background
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Synonyms
SLAC2-A
Gene Name
Melanophilin
Gene ID
79083
UniProt
Q9BV36
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MLPH
Overview
MLPH mouse monoclonal antibody, clone LBI6E3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=79083
Uniprot URL
https://www.uniprot.org/uniprot/Q9BV36
Curated Selection
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