UBE2D2 Mouse Monoclonal Antibody [Clone ID: LBI1A9]
Product Specifications
Background
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub) -proteasome system (UPS) . An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5) . Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Synonyms
E2 (17) KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B
Gene Name
Ubiquitin conjugating enzyme E2 D2
Gene ID
7322
UniProt
P62837
Conjugation
Unconjugated
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
1 mg/ml
Dilution
IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
UBE2D2
Overview
UBE2D2 mouse monoclonal antibody, clone LBI1A9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7322
Uniprot URL
https://www.uniprot.org/uniprot/P62837
Curated Selection
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