Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI10C5]
Product Specifications
Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Overview
SMPD1 mouse monoclonal antibody, clone LBI10C5
Synonyms
ASM; ASMASE; NPD
Gene Name
Sphingomyelin phosphodiesterase 1
Gene ID
6609
UniProt
P17405
Conjugation
Unconjugated
Related Pathways
Lysosome, Metabolic pathways, Sphingolipid metabolism
Field of Research
Lysosome, Metabolic pathways, Sphingolipid metabolism
Concentration
1 mg/ml
Dilution
WB 1:200
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SMPD1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6609
Uniprot URL
https://www.uniprot.org/uniprot/P17405
Frequently Asked Questions
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