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Neuraminidase (NEU1) Mouse Monoclonal Antibody [Clone ID: LBI3D4]

Product Specifications

Background

The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]

Synonyms

NANH; NEU; SIAL1

Gene Name

Neuraminidase 1 (lysosomal sialidase)

Gene ID

4758

UniProt

Q99519

Conjugation

Unconjugated

Related Pathways

Lysosome, Other glycan degradation, Sphingolipid metabolism

Field of Research

Lysosome, Other glycan degradation, Sphingolipid metabolism

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

NEU1

Overview

NEU1 mouse monoclonal antibody, clone LBI3D4

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4758

Uniprot URL

https://www.uniprot.org/uniprot/Q99519

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