CANX Antibody (C-Term) [APR33574G]
Product Specifications
Synonyms
Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90, CANX
Gene Name
CANX
Gene ID
821
UniProt
P27824
Chromosomal Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065) . The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232) .
Applications
WB, FC, IHC-P
Dilution
IHC-P--1:100~500 FC--1:25 WB--1:2000
Function
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Molecular Weight
67568
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CANX Antibody (C-Term) [APR33574G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=821
Uniprot URL
https://www.uniprot.org/uniprot/P27824
Available Sizes
Curated Selection
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