(DANRE) rho Antibody (N-Term) [APR33110G]

Tissue Location: Retinal rod photoreceptor cells, predominantly in the outer segments (at protein level) (PubMed:10349976) . Retinal rod photoreceptor cells (PubMed:8327475, PubMed:8603882)

Membrane {ECO:0000250|UniProtKB:P08100}; Multi- pass membrane protein {ECO:0000250|UniProtKB:P08100}. Cell projection, cilium, photoreceptor outer segment Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia. {ECO:0000250|UniProtKB:P08100}

Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity) . Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity) .

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (DANRE) rho Antibody (N-Term) [APR33110G].