HIST1H1B Antibody (N-term) [APR32141G]
Product Specifications
Background
Tissue Location: Ubiquitous. Expressed in the majority of the cell lines tested and in testis.
Synonyms
Histone H15, Histone H1a, Histone H1b, Histone H1s-3, HIST1H1B, H1F5
Gene Name
HGNC:4719
Gene ID
3009
UniProt
P16401
Chromosomal Location
Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin
Applications
FC, WB
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) .
Molecular Weight
22580
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HIST1H1B Antibody (N-term) [APR32141G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3009
Uniprot URL
https://www.uniprot.org/uniprot/P16401
Available Sizes
Curated Selection
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