EFTUD1 Antibody (C-term) [APR30594G]
Product Specifications
Background
Tissue Location: Expressed at low levels in brain. Expression is highly increased in glioma tissues.
Synonyms
Elongation factor Tu GTP-binding domain-containing protein 1, Elongation factor-like 1, Protein FAM42A, EFTUD1, EFL1, FAM42A
Gene Name
HGNC:25789
Gene ID
79631
UniProt
Q7Z2Z2
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Molecular Weight
125430
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EFTUD1 Antibody (C-term) [APR30594G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=79631
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z2Z2
Available Sizes
Curated Selection
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