MCP110

MCP110 is an inhibitor of Ras/Raf-1 interaction. MCP110 blocks the interaction of Ras with Raf. MCP110 disrupts this interaction might can be used for the research of human tumors[1].

Product Specifications

CAS Number

[521310-51-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Raf; Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mcp110.html

Purity

99.82

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(N(CC1=CC=C(OCC2=CC=CC=C2)C(OC)=C1)CCC3=NC=CC=C3)CCCCC4=CC=CC=C4

Molecular Formula

C33H36N2O3

Molecular Weight

508.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Juran Kato-Stankiewicz, et al. Inhibitors of Ras/Raf-1 Interaction Identified by Two-Hybrid Screening Revert Ras-dependent Transformation Phenotypes in Human Cancer Cells. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14398-403.