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MRPS16 Antibody - C-terminal region: HRP (ARP66866_P050-HRP)

Product Specifications

Gene Aliases

COXPD2, RPMS16, CGI-132, MRP-S16

Gene ID

51021

Swiss Prot

Q9Y3D3

Accession Number

NP_057149

Host

Rabbit

Reactivity

Human, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPS16

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described.

Partner Proteins

CEP76; UBC; HNRNPU; MRPS9; MRPS26; MRPS25; MRPS2; MCAT; FAM50B; HNRNPR; HNRNPDL; SSBP1; PSMC2; PSMC1; PSMA7; PSMA5; MPV17; SLC25A5; ATXN10; CAND1; ZP3; ELAVL1; ICT1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Guinea Pig: 75%; Human: 100%; Rat: 75%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

137

NCBI Gene Symbol

MRPS16

Protein Name

28S ribosomal protein S16, mitochondrial

Nucleotide Accession Number

NM_016065

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