INVS Antibody: FITC (ARP63318_P050-FITC)
Product Specifications
Gene Name
Inversin
Gene Aliases
INV, NPH2, NPHP2
Gene ID
27130
Swiss Prot
Q9Y283
Accession Number
NP_055240
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence CVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRR
Target
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Partner Proteins
ZNF512B; CEP164; DDB1; UBC; CALM2; NPHP1; HIF1AN
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
118 kDa
Shipping Conditions
Wet Ice
Protein Length
1065
NCBI Gene Symbol
INVS
Protein Name
Inversin
Nucleotide Accession Number
NM_014425
Curated Selection
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