DRD3 Antibody - C-terminal region: Biotin (ARP63162_P050-Biotin)
Product Specifications
Gene Name
Dopamine receptor D3
Gene Aliases
D3DR, ETM1, FET1
Gene ID
1814
Swiss Prot
P35462
Accession Number
NP_387512
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig
Target
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD) .
Partner Proteins
SLC9A3; USP48; EEF1G; CLIC6; MPDZ; EPB41L2; GIPC1; NCS1; EPB41L1; EEF1B2; NCK1; FLNA; GNAI1; EPB41; GRB2; RDX
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 77%; Dog: 86%; Guinea Pig: 75%; Horse: 79%; Human: 100%; Pig: 79%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
41kDa
Shipping Conditions
Wet Ice
Protein Length
367
NCBI Gene Symbol
DRD3
Protein Name
D (3) dopamine receptor
Nucleotide Accession Number
NM_033663
Curated Selection
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