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NUP153 Antibody - C-terminal region: HRP (ARP61446_P050-HRP)

Product Specifications

Gene Name

Nucleoporin 153kDa

Gene Aliases

N153, HNUP153

Gene ID

9972

Swiss Prot

P49790

Accession Number

NP_005115

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.

Partner Proteins

UBC; HDAC11; LMNA; ESR1; PNPT1; DPY30; FIP1L1; NUP107; NUP54; NUP50; NCAPD2; PRKCSH; MEA1; EIF4B; EEF1B2; CSTF2; C1QBP; CUL3; SIRT7; RANBP2; CTNNB1; XPO7; SUMO2; SMAD3; SUMO1; MAPK3; MAPK1; Mki67; Kifc5b; MYC; KPNB1; tat; APC; USP20; USP11; TPR; SENP2; XP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

162kDa

Shipping Conditions

Wet Ice

Protein Length

1475

NCBI Gene Symbol

NUP153

Protein Name

Nuclear pore complex protein Nup153

Nucleotide Accession Number

NM_005124

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