SETD2 Antibody - N-terminal region: Biotin (ARP47617_T100-Biotin)
Product Specifications
Gene Name
SET domain containing 2
Gene Aliases
LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP
Gene ID
29072
Swiss Prot
Q9BYW2
Accession Number
AAH72440
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2
Target
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Partner Proteins
CLK2; SOX2; CBX8; HCVgp1; SIAH2; SMAD3; CIC; ATXN1; ELAVL1; UBC; SETD2; HIST1H3A; POLR2A; TP53; IWS1; HTT
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
SETD2 is strongly supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Dog: 86%; Horse: 86%; Human: 100%; Mouse: 83%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
97kDa
Shipping Conditions
Wet Ice
Protein Length
891
NCBI Gene Symbol
SETD2
Protein Name
Histone-lysine N-methyltransferase SETD2
Nucleotide Accession Number
NM_014159
Curated Selection
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