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TYR Antibody - middle region : FITC (ARP44269_T100-FITC)

Selected Variant

ARP44269_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Tyrosinase (oculocutaneous albinism IA)

Gene Aliases

ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3

Gene ID

7299

Swiss Prot

P14679

Accession Number

NP_000363

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TYR

Target

TYR is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. It catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

Partner Proteins

SYVN1; UBC; TYRP1; RB1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Goat: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Bidinost, C., (2006) Invest. Ophthalmol. Vis. Sci. 47 (4), 1486-1490

Shipping Conditions

Wet Ice

Protein Length

529

NCBI Gene Symbol

TYR

NCBI GB Accession Number

TYR

Host or Source

Rabbit

Protein Name

Tyrosinase

Nucleotide Accession Number

NM_000372

Peptide Sequence

CLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYM

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