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MAF Antibody - C-terminal region: Biotin (ARP38608_P050-Biotin)

Product Specifications

Gene Name

V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

Gene Aliases

CCA4, AYGRP, c-MAF, CTRCT21

Gene ID

4094

Swiss Prot

O75444-1

Accession Number

NP_005351

Host

Rabbit

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAF

Target

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4) . Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MAFB; FOSL1; MAF; FOS; ATF4; AHR; SUMO1; UBE2I; PML; SIN3A; HDAC2; SMARCA5; CEBPA; KDM5B; MAFA; SOX9; EP300; MAFG; USF2; CREBBP; MYB; JUN; ETS1; HOXD12

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Horse: 93%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

403

NCBI Gene Symbol

MAF

Protein Name

Transcription factor Maf

Nucleotide Accession Number

NM_005360

Curated Selection

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