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POLE3 Antibody - N-terminal region: Biotin (ARP33054_T100-Biotin)

Product Specifications

Gene Name

Polymerase (DNA directed), epsilon 3 (p17 subunit)

Gene Aliases

P17, YBL1, CHRAC2, CHRAC17, CHARAC17

Gene ID

54107

Swiss Prot

Q9NRF9

Accession Number

NP_059139

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3

Target

POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

Partner Proteins

CHRAC1; DRAP1; DR1; UBC; NANS; ANXA6; gag-pol; POLE4; CPSF2; POLE; APP; YEATS2; POLE2; Cebpb; SUMO2; XRCC5; BAZ1A; SMARCA5; RAD17

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

POLE3 is supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

Shipping Conditions

Wet Ice

Protein Length

147

NCBI Gene Symbol

POLE3

Protein Name

DNA polymerase epsilon subunit 3

Nucleotide Accession Number

NM_017443

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