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SPI1 Antibody - N-terminal region: Biotin (ARP31420_P050-Biotin)

Product Specifications

Gene Name

Spi-1 proto-oncogene

Gene Aliases

OF, PU.1, SFPI1, SPI-1, SPI-A

Gene ID

6688

Swiss Prot

P17947

Accession Number

NP_001074016.1

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human SPI1

Target

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

Shipping Conditions

Wet Ice

Protein Length

245

NCBI Gene Symbol

SPI1

Protein Name

Transcription factor PU.1

Nucleotide Accession Number

NM_001080547.1

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