PFI-90
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1) .
Product Specifications
CAS Number
[53995-62-3]
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Apoptosis; Histone Demethylase
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pfi-90.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=NC=CC=C1)NNC2=NC=CC=C2
Molecular Formula
C11H10N4O
Molecular Weight
214.22
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM3
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
EHD4 (EH Domain-Containing Protein 4, Hepatocellular Carcinoma-Associated Protein 10/11, PAST Homolog 4, EHD4, HCA10, HCA11, PAST4) (MaxLight 750)
EHD4 (EH Domain-Containing Protein 4, Hepatocellular Carcinoma-Associated Protein 10/11, PAST Homolog 4, EHD4, HCA10, HCA11, PAST4) (MaxLight 750)
