Ac-LEHD-AMC
Product Specifications
UNSPSC Description
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].
Target Antigen
Caspase
Type
Dye Reagents
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-lehd-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O
Molecular Weight
711.72
References & Citations
[1]Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151(3):299-316.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1652/Ac-LEHD-AMC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1652/
Clinical Information
No Development Reported
CAS Number
292633-16-0
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